Summary Questions About DHA-EE in Zellweger’s
Modulation of inflammation in brain: a matter of fat
Akhlaq A. Farooqui , Lloyd A. Horrocks, Tahira Farooqui
Journal of Neurochemistry, January 25, 2007
https://doi.org/10.1111/j.1471-4159.2006.04371.x
Essential Dietary Bioactive Lipids in Neuroinflammatory Diseases. Antioxid Redox Signal.
Catani MV, Gasperi V, Bisogno T, Maccarrone M.
2018;29(1):37–60. doi:10.1089/ars.2016.6958
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984567/?report=reader
Dra. Manuela Martinez‘ last published research, 2010. The Δ4-desaturation pathway for
DHA biosynthesis is operative in the human species: Differences between normal controls
and children with the Zellweger syndrome. Martinez et al. Lipids in Health and Disease 2010,
9:98 http://www.lipidworld.com/content/9/1/98
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949860/
Docosahexaenoic acid mediates peroxisomal elongation, a prerequisite for peroxisome division.
(2-2012) http://jcs.biologists.org/content/125/3/589.long#T1
DHA is a key factor in stimulating brain-derived neurotrophic factor (BDNF)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208643/
http://www.researchgate.net/publication/26695415
https://www.ibp.ucla.edu/research/GomezPinilla/publications/Diet1457.pdf
Noguer Visual Follow-Up in Peroxisomal-Disorder Patients Treated with Docosahexaenoic Acid
Ethyl Ester http://www.ncbi.nlm.nih.gov/pubmed/19933185
Martínez, Manuela, et al. “Therapeutic effects of docosahexaenoic acid ethyl ester in patients with
generalized peroxisomal disorders.” The American Journal of Clinical Nutrition 71.1 (2000):
376s-385s. http://www.ncbi.nlm.nih.gov/pubmed/10618001
http://ajcn.nutrition.org/content/71/1/376s.full
Zellweger’s Syndrome Restoring the DHA Levels in the Brains of Zellweger Patients, J Mol Neurosci.
2001 Apr-Jun;16(2-3):309-16 http://www.ncbi.nlm.nih.gov/pubmed/11478386
The fundamentals and practice of docosahexaenoic acid therapy in peroxisomal disorders, by M
Martinez – 2000. Current Opinion in Clinical Nutrition & Metabolic Care: March 2000 – Volume 3 –
Issue 2 – pp 101-108.
http://journals.lww.com/coclinicalnutrition/Abstract/2000/03000/The_fundamentals_and_practice_of_docosahexaenoic.4.aspx
Peroxisomal disorders and their treatment.
http://www.momtahan.com/mmartinez/
Two Studies, Two Products, Two Results Investigates the difference in the Martinez studies and the Paker, et al. study.