Summary of clinical and biochemical changes from DHA-EE in Peroxisomal Biogenesis Disorders, Zellweger’s Syndrome

Summary of DHA-EE benefits for Peroxisomal Biogenesis Disorders, Zellweger’s Syndrome.

DHA-EE effects

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The chart from Dra. Martinez research shows that 100% of the children taking DHA-EE had significant correction in DHA levels, 76% improved their plasmalogen ratios, 60% showed a drop in VLCFA’s, 92% substantially lower liver function tests, 56% had vision and muscle tone recovery, and 62.5% had noticeable positive changes in their MRI’s.

Later Martinez research in summary table of biochemical and clinical evolution in twenty patients with Peroxisomal Biogenesis Disorder, Zellweger’s Syndrome, treated with DHA-EEshowed 100% of the children had improvement in DHA levels and in liver function.

Follow-up Test                                          Improvement
DHA                                                              20/20
VLCFA ratios                                               18/20
Plasmalogen ratios                                   12/20
Liver enzyme tests                                     20/20
Vision                                                            12/20
Social Contact                                             17/20
Muscle tone                                                 13/20
MRI                                                                 9/12

1Restoring the DHA levels in the brains of Zellweger patients. Martinez M. J Mol Neurosci. 2001 Apr-Jun;16(2-3):309-16; discussion 317-21.