DHA-EE Research

Summary Questions About DHA-EE in Zellweger’s

Dra. Manuela Martinez‘ last published research, 2010.  The Δ4-desaturation pathway for DHA biosynthesis is operative in the human species: Differences between normal controls and children with the Zellweger syndrome. Martinez et al. Lipids in Health and Disease 2010, 9:98
http://www.lipidworld.com/content/9/1/98
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949860/

Docosahexaenoic acid mediates peroxisomal elongation, a prerequisite for peroxisome division.  (2-2012)
http://jcs.biologists.org/content/125/3/589.long#T1

DHA is a key factor in stimulating brain-derived neurotrophic factor (BDNF)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208643/

http://www.researchgate.net/publication/26695415 

https://www.ibp.ucla.edu/research/GomezPinilla/publications/Diet1457.pdf

Noguer Visual Follow-Up in Peroxisomal-Disorder Patients Treated with Docosahexaenoic Acid Ethyl Ester
http://www.ncbi.nlm.nih.gov/pubmed/19933185

Martínez, Manuela, et al. “Therapeutic effects of docosahexaenoic acid ethyl ester in patients with generalized peroxisomal disorders.” The American Journal of Clinical Nutrition 71.1 (2000): 376s-385s.
http://www.ncbi.nlm.nih.gov/pubmed/10618001
http://ajcn.nutrition.org/content/71/1/376s.full

Zellweger’s Syndrome Restoring the DHA Levels in the Brains of Zellweger Patients, J Mol Neurosci. 2001 Apr-Jun;16(2-3):309-16
http://www.ncbi.nlm.nih.gov/pubmed/11478386

The fundamentals and practice of docosahexaenoic acid therapy in peroxisomal disorders, by M Martinez – ‎2000.  Current Opinion in Clinical Nutrition & Metabolic Care: March 2000 – Volume 3 – Issue 2 – pp 101-108.
http://journals.lww.com/co-clinicalnutrition/Abstract/2000/03000/The_fundamentals_and_practice_of_docosahexaenoic.4.aspx

Peroxisomal disorders and their treatment.
http://www.momtahan.com/mmartinez/

Textbooks:
Enfermedades peroxisomales generalizadas: nuevas posibilidades terapeuticas, Martinez Cap 44;
Enfermedades peroxisomales generalizadas: nuevo enfoque terapeutico, Cap.+68.+Dra.+Martinez;

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